The AMMA collection has its origins in the tradition and legacy of its two founding members, whose family has encouraged collecting, and the creation of museum spaces and cultural projects. The example set by Don Manuel Espinosa Yglesias and one of the patrons of preserving modern Mexican works of art, guided AMMA to continue the family practice by the formation of its contemporary international art collection.

Since the beginning of the 21th century, AMMA has acquired artworks both by emerging and established artists, and Mexican and foreign, gradually creating a collection of contemporary art, which includes figurative paintings and sculptures in its majority, with aesthetics referring to contemporary culture and mass media, sometimes alluding to hyperrealism and pop art. It also includes expressionist works due to its manufacture, brush stroke and gesture. The central themes of the collection are portrait and the human figure, represented through different means and style. To a lesser extent it also includes abstract painting and contemporary landscape.

As part of the family legacy, Fundación AMMA also keeps a collection of popular art consisting of 50 biblical passages from the Old and New Testaments with a thousand of polychromatic clay figures made by Felipe Nieva, a craftsman from the Mexican State of Veracruz, during the first half of the 20th century.